An educational and information resource on the science of aging

Amaranth flower

"The knowledge that every ambition is doomed to frustration at the hands of a skeleton have never prevented the majority of human beings from behaving as though death were no more than an unfounded rumor."

Aldous Huxley

Aging, or senescence, is the major cause of suffering, disease, and death in modern times. With the worldwide graying of the population, we are now aging for a longer period of time than ever before. Gerontology, and its sub-field biogerontology in particular, is the science that studies the aging process to prevent age-related disease and degeneration, preserve health, and prolong human life. landeng官网专业破解版 aims to highlight the importance of research on aging and give an overview of current knowledge on the biology and genetics of aging, including anti-aging therapies, models and theories of aging. The most ambitious, even if distant, goal of gerontological research is to make aging optional, to develop a cure for aging, and the social implications of a radical increase in human lifespan due to scientific breakthroughs are also discussed. is aimed at a vast audience and includes lanter 破解版 for the non-specialist. Though of course my personal points of view are more prevalent, I try to mention different perspectives, even if I do not agree with them. Although is not peer-reviewed, it is used as a reference by scientists and students in the field and recognized as a major knowledge and information website on the aging process; as evidence of its academic standing, has been highlighted in landeng破解版安卓版5.0.1 (307:187), Aging Cell (8:65) and Nucleic Acids Research (41:D1027).


Why I study aging, what is on offer at, my goals for this website, and how best to use its resources.

  • Integrative Genomics of Ageing Group; describes our lab's work.


An introduction to work done in the biology of aging, its importance, potential implications and career advice.

  • Caloric Restriction reviews and discusses CR facts and products trying to mimic its effects.


An overview of current research on the biology of human aging featuring key observations, concepts, and theories. Thanks to David Bahry, available is also a printer-friendly version (last updated in August 2013).

  • Comparative Biology of Aging presents trends found in comparative studies of aging.

  • Cellular Senescence; cellular models of aging and the rationale behind them.

  • Telomeres and Telomerase presents the telomeres, their maintenance mechanisms, and their relation to human aging.

  • Damage-Based Theories of Aging introduces and discusses theories of aging based on damage accumulation.

  • Programmed Theories of Aging introduces and discusses theories of aging based on programmed events.

  • Strategies for Engineered Negligible Senescence or SENS is a proposal to cure aging which is appraised here.


I am the principal investigator of the Integrative Genomics of Ageing Group at the University of Liverpool in the UK. Amongst other projects, we maintain the Human Ageing Genomic Resources, a series of tools and databases aimed at understanding the genetic basis of human aging.

  • GenAge is a curated database of genes related to aging in humans and in model organisms.

  • GenDR is the first database of dietary restriction-associated genes.

  • LongevityMap is the first database of human genetic variants associated with longevity.

  • AnAge is an aging-oriented animal database featuring over 4,000 species.

  • The Digital Ageing Atlas is the first centralized collection of aging changes and pathologies.

Human Ageing Genomic Resources

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Creation date: Circa 1997
Last modified: June 26, 2018

Thank you for visiting my website. Please feel free to contact me if you have any questions, ideas, comments or suggestions.

Copyright © 1997 - 2014, 2018 by João Pedro de Magalhães. All rights reserved.